Searchable abstracts of presentations at key conferences in endocrinology

ea0035p54 | Adrenal cortex | ECE2014

Effects of non-physiological concentrations of glucocorticoids on apoptotic cell death of human early hematopoietic stem/progenitor cells: in vitro studies

Kawa Milosz , Piecyk Katarzyna , Sobus Anna , Michalska Agata , Roginska Dorota , Ustianowski Przemyslaw , Syrenicz Anhelli , Machalinski Boguslaw

Objectives: Glucocorticoids (GCs) intervene in different physiological activities in almost all systems of the human organism. However, GCs are also potent inducers of apoptosis in many cell types and tissues. It is known, that glucocorticoid-induced apoptosis affects the musculoskeletal system, circulatory system, nervous system, endocrine system, reproductive system, and the immune system. Nevertheless, the exact mechanisms of GCs action in human normal hematopoiesis are sti...